Stage 0 TNM T1, N0, M0 Carcinoma in situ—a very early, microscopic, non-invasive cancer that has not spread below the membrane of the first layer of anal tissue . Standard Treatment Surgical removal of the tumor . Five-Year Survival 100 percent Stage I TNM T1, N0, M0 A tumor less than 2 cm (1 in.) with no evidence of spread to lymph nodes or other organs. Standard Treatment Small tumors of the skin around the anus and superficial well-differentiated cancers of the anal canal may be adequately treated by local excision with preservation of the sphincter muscle, with or without radiation therapy .